Question Question 1 2 / 2 pts In hemolytic anemia, jaundice occurs only when the patient has elevations in aspartate transaminase (AST) and alanine transaminase (ALT) . heme destruction exceeds the liver’s ability to conjugate and excrete bilirubin . the erythrocytes are coated with an immunoglobulin . erythrocytes are destroyed in the spleen . Question 2 2 / 2 pts Symptoms of polycythemia vera are mainly the result of destruction of erythrocytes . neurologic involvement . increased blood viscosity . a decreased erythrocyte count . Question 3 2 / 2 pts The underlying disorder of _____ anemia is defective secretion of intrinsic factor, which is essential for the absorption of vitamin B12 . pernicious microcytic hypochromic hemolytic Question 4 2 / 2 pts Pernicious anemia generally requires continued therapy lasting 8 to 12 months . the rest of one’s life . until the iron level is normal . 6 to 8 weeks . Question 5 2 / 2 pts In some anemias, the erythrocytes are present in various sizes, which is referred to as microcytosis . poikilocytosis . isocytosis . anisocytosis . Question 6 2 / 2 pts Untreated pernicious anemia is fatal, usually because of renal failure . heart failure . brain hypoxia . liver hypoxia . Question 7 0 / 2 pts Local signs and symptoms of Hodgkin disease–related lymphadenopathy are a result of inflammation and ischemia . obstruction and pressure . ischemia and pressure . pressure and obstruction . Question 8 2 / 2 pts What is the most common cause of vitamin K deficiency? An IgG-mediated autoimmune disorder Liver failure Total parenteral nutrition (TPN) with antibiotic therapy Administration of warfarin (Coumadin) Question 9 2 / 2 pts Heparin-induced thrombocytopenia (HIT) is described as a(n) IgG immune-mediated adverse drug reaction that reduces circulating platelets . hematologic reaction to heparin in which the bone marrow is unable to produce sufficient platelets to meet the body’s needs . cell-mediated drug reaction in which macrophages process the heparin and platelet complexes that are then destroyed by activated cytotoxic T cells . IgE-mediated allergic drug reaction that reduces circulating platelets . Question 10 2 / 2 pts Which proinflammatory cytokines are responsible for the development and maintenance of DIC? Tumor necrosis factor-alpha (TNF-a); IL-1, IL-6, and IL-8; and platelet-activatingfactor (PAF) Granulocyte-macrophage colony-stimulating factor (GM-CSF); IL-3, IL-5, and IL-9, and IFN-? Granulocyte colony-stimulating factor (G-CSF); IL-2, IL-4, and IL-10; and IFN-? Macrophage colony-stimulating factor (M-CSF); IL-7, IL-11, and IL-14; and PAF Question 11 2 / 2 pts G6PD and sickle cell disease are diagnosed equally in men and women . inherited autosomal recessive disorders . inherited X-linked recessive disorders . disorders initiated by hypoxemia and acidosis . Question 12 2 / 2 pts The sickle cell trait differs from sickle cell disease in that the child with sickle cell trait has the mildest form of the disease with normal hemoglobin and hemoglobin F, which prevents sickling . has a mild form of sickle cell disease that causes sickling during fever and infection, but not during acidosis or hypoxia, whereas the child with sickle cells disease develops sickling during each of these conditions . has a milder form of the disease that is characterized by vaso-occlusive crises and is believed to result from higher hemoglobin values and viscosity . inherited normal hemoglobin A from one parent and Hb S from the other parent, whereas the child with sickle cell disease has Hb S from both parents . Question 13 2 / 2 pts Hemolytic disease of the newborn can occur if the mother is type AB blood and the fetus has type B . Rh-positive and the fetus is Rh-negative . Rh-negative and the fetus is Rh-positive . type A blood and the fetus has type O . Question 14 2 / 2 pts What is the name of the disorder in which levels of bilirubin remain excessively high in the newborn and are deposited in the…
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